HEMOCLOT Quanti. V-L

Description

Clotting method for the quantitative measurement of Factor V Leiden concentration in citrated plasma, by its resistance to the action of activated protein C (APC). The assay is performed in the presence of activated protein C and protein S (one single test for each patient). In the presence of APC, the prolongation of clotting time is an inverse relationship of the concentration of Factor V Leiden (mutation R506Q). Normal factor V is not measured.

Intended use

Quantitative measurement of Factor V Leiden, resistant to the action of activated protein C (APC resistance), for diagnosing patients carrying the R506Q FV mutation (Factor V Leiden), or any FV mutant resistant to APC.