CoaChrom® Factor XI
Description
This kit is designed for the measurement of factor XI (FXI) in human plasma. Plasma is treated with acetone to destroy inhibitors of αFXIIa and FXIa. The contact system is then activated with kaolin, during which FXIIa converts FXI to FXIa. Following the activation step, FXIIa and kallikrein are inhibited, and the FXIa level is determined by its ability to cleave a chromogenic substrate and releases p‐nitroaniline (pNA). This can be measured photometrically, and is proportional to the FXI concentration.
Intended use
Measurement of factor XI (FXI) in human plasma. For research use only.