ZYMUTEST TAFI (Total) Antigen

Description

Two-site ELISA method for the measurement of TAFI (total) antigen (thrombin activatable fibrinolysis inhibitor). Assay designed with a murine monoclonal antibody specific for TAFI, for coating, and a goat polyclonal antibody labelled with a horseradish peroxidase (HRP) marker. Assay calibrator has a defined concentration of TAFI Ag, expressed as % of normal pooled human plasma and exactly determined with three selected human plasma pools. TAFI and TAFIa are identically measured.

Intended use

High TAFI Ag concentrations involve a hypofibrinolytic status, which can induce an elevated risk of thrombosis. Measurement of TAFI Ag on plasma in order to diagnose a risk of a hypofibrinolysis resulting from an excess of TAFI.