ZYMUTEST Free Protein S
Description
Two-site ELISA method for the measurement of Free Protein S (form which supports the anticoagulant activity), in human citrated plasma. Assay designed with two conformational murine monoclonal antibodies, non calcium dependent, the first one for coating the microplate (immunocapture) and the second one, labelled with a horse radish Peroxidase (HRP) marker.
Intended use
Diagnosis of protein S deficiencies (congenital, acquired or transitory).
• Type I deficiency: Partial deficiency of total and free protein S antigen.
• Type II deficiency: Normal total and free protein S antigen, reduced activity.
• Type III deficiency: Normal total antigen, decreased activity and free antigen. Assay of protein S in clinical studies.