ZYMUTEST Protein S Total
Description
Two-site ELISA method for the measurement of total protein S (free or complexed with C4b-BP), in human citrated plasma.
Assay designed with two conformational murine monoclonal antibodies, calcium dependent, the first one for coating the microplate (immunocapture) and the second one, labelled with a horseradish peroxidase (HRP) marker.
Intended use
Diagnosis of protein S deficiencies (congenital, acquired or transitory)
• Type I deficiency: Partial deficiency of total and free protein S antigen
• Type II deficiency: Normal total and free protein S antigen, reduced activity
• Type III deficiency: Normal total antigen, decreased activity and free antigen, assay of protein S in clinical studies.